基因名：
PRAME
产品别名：
CT130； MAPE； OIP-4； OIP4； PRAME； PRAME nuclear receptor transcriptional regulator； PRAME nuclear receptor transcriptional regulator； melanoma antigen preferentially expressed in tumors； Opa-interacting protein OIP4； cancer/testis antigen 130； opa-interacting protein 4； preferentially expressed antigen in melanoma； preferentially expressed antigen of melanoma； 黑色素瘤优先表达抗原； 黑色素瘤优先表达抗原(PRAME)；
背景信息：
This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
