基因名：
BACE1
产品别名：
ASP2； BACE； HSPC104； BACE1； beta-secretase 1； beta-secretase 1； beta-secretase 1； APP beta-secretase； asp 2； aspartyl protease 2； beta-site APP cleaving enzyme 1； beta-site APP-cleaving enzyme； beta-site amyloid beta A4 precursor protein-cleaving enzyme； memapsin-2； membrane-associated aspartic protease 2； transmembrane aspartic proteinase Asp2； β-位淀粉样前体蛋白裂解酶1(bACE1)； β分泌酶； 磷酸化β分泌酶；
背景信息：
Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells.BACE-1 is the peptidase predominantly responsible for cleavage of the amyloid precursor protein beta site in the brain to generate the amyloid beta peptide. Because the amyloid beta peptide is a major component of amyloid plaques, BACE-1 has been implicated in the onset and/or progression of Alzheimer's disease. BACE-1 is expressed in a variety of human tissues,such brain, pancreatic tissue.
