基因名：
HSPBP1
产品别名：
FES1； HSPBP1； HSPA (Hsp70) binding protein 1； HSPA (Hsp70) binding protein 1； hsp70-binding protein 1； HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1； heat shock protein-binding protein 1； hsp70 interacting protein； 70kDa热休克蛋白结合蛋白1(HSPBP1)； 热休克蛋白70结合蛋白1；
背景信息：
Hsp70-interacting protein (HspBP1) belongs to a family of eukaryotic proteins identified as nucleotide exchange factors for Hsp70, which exhibit varying degrees of compartment and species specificity. HspBP1 interferes with the CHIP-induced degradation of immature forms of the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates CFTR maturation. HspBP1 binds to Hsp70, inhibits its activity and promotes dissociation of nucleotides from the Hsp70 ATPase domain. It is a protein mainly expressed in heart and skeletal muscle.
