基因名:
GABARAPL1
产品别名:
APG8-LIKE; APG8L; ATG8; ATG8B; ATG8L; GEC1; GABARAPL1; GABA type A receptor associated protein like 1; GABA type A receptor associated protein like 1; gamma-aminobutyric acid receptor-associated protein-like 1; GABA(A) receptor-associated protein-like 1; early estrogen-regulated protein; glandular epithelial cell protein 1; γ氨基丁酸受体相关蛋白样1;
背景信息:
Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1 (GABARAPL1) is a cytoplasmic protein that belongs to the MAP1 LC3 family. GABARAPL1 is expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta, and skeletal muscle. It can interact with GABRG2, OPRK1 and β-Tubulin. GABARAPL1 increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.