重组IL-1相关Ig受体蛋白

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重组IL-1相关Ig受体蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组单Ig IL1相关受体(SIGIRR)蛋白
Recombinant Sigirr

基因名：

Sigirr

产品别名：

AI256711； TIR8； Sigirr； single immunoglobulin and toll-interleukin 1 receptor (TIR) domain； single immunoglobulin and toll-interleukin 1 receptor (TIR) domain； single Ig IL-1-related receptor； single Ig IL-1 receptor related protein； single Ig IL-1R-related molecule； single Ig IL-1R-related protein； single immunoglobulin domain-containing IL1R-related protein； toll/interleukin-1 receptor 8； IL-1相关Ig受体；单Ig IL1相关受体(SIGIRR)；

背景信息：

Single Ig IL-1-related receptor SIGIRR, also designated single immunoglobulin domain-containing IL-1R-related protein or Toll/interleukin-1 receptor 8 (TIR8), is a member of the interleukin-1 receptor family. SIGIRR acts as a negative regulator of the IL-1R and Toll-like receptor signaling pathways and reduces the recruitment of certain components to the TLR4 receptor. Subsequently, SIGIRR confers resistance to P. aeruginosa corneal infection. SIGIRR can form complexes with IL-1R1, MYD-88, IRAK-1 and TRAF-6 upon IL-1 stimulation and TLR4 after LPS stimulation. It is a single-pass type III membrane protein that is mainly expressed in kidney, lung and gut.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。