基因名:
Spry4
产品别名:
A030006O18Rik; sprouty4; Spry4; sprouty RTK signaling antagonist 4; sprouty RTK signaling antagonist 4; protein sprouty homolog 4; 侧支发芽因子同源物4(SPRY4); 快速发育生长因子同源蛋白4;
背景信息:
SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).[supplied by OMIM, Mar 2008]