基因名：
PRDX5
产品别名：
ACR1； AOEB166； B166； HEL-S-55； PLP； PMP20； PRDX6； PRXV； SBBI10； prx-V； PRDX5； peroxiredoxin 5； peroxiredoxin 5； peroxiredoxin-5, mitochondrial； Alu co-repressor 1； TPx type VI； antioxidant enzyme B166； epididymis secretory protein Li 55； liver tissue 2D-page spot 71B； peroxiredoxin V； peroxisomal antioxidant enzyme； thioredoxin peroxidase PMP20； thioredoxin reductase； thioredoxin-dependent peroxiredoxin 5； 硫氧还蛋白还原酶； 过氧化还原酶5(PRDX5)；
背景信息：
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.
