基因名：
ASF1A
产品别名：
CGI-98； CIA； HSPC146； ASF1A； anti-silencing function 1A histone chaperone； anti-silencing function 1A histone chaperone； histone chaperone ASF1A； ASF1 anti-silencing function 1 homolog A； CCG1-interacting factor A； anti-silencing function protein 1 homolog A； hAsf1； hAsf1a； hCIA； 细胞衰老相关蛋白ASF1A；
背景信息：
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
