基因名:
ABI3BP
产品别名:
NESHBP; TARSH; ABI3BP; ABI family member 3 binding protein; ABI family member 3 binding protein; target of Nesh-SH3; ABI family, member 3 (NESH) binding protein; ABI gene family member 3-binding protein; ABI gene family, member 3 (NESH) binding protein; nesh-binding protein; ABI基因家族成员3结合蛋白;
背景信息:
ABI3BP (ABI gene family member 3-binding protein) contains 2 fibronectin type-III domains and is thought to interact with ABI3. It is expressed in brain, heart, lung, liver, pancreas, kidney and placenta. ABI3BP expression is dramatically reduced in human lung cancer cell lines and primary lung tumor, while it is predominantly expressed in normal conditions, suggesting that it is involved in prevention of tumorigenesis.