基因名:
NSL1
产品别名:
C1orf48; DC8; MIS14; NSL1; NSL1 component of MIS12 kinetochore complex; NSL1 component of MIS12 kinetochore complex; kinetochore-associated protein NSL1 homolog; NSL1, MIND kinetochore complex component, homolog; NSL1, MIS12 kinetochore complex component; 着丝粒相关蛋白NSL1;
背景信息:
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X. [provided by RefSeq, Jul 2014]