重组NOC2家族样蛋白

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重组NOC2家族样蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant NOC2L
Recombinant NOC2 like nucleolar associated transcriptional repressor protein

基因名：

NOC2L

产品别名：

NET15； NET7； NIR； PPP1R112； NOC2L； NOC2 like nucleolar associated transcriptional repressor； NOC2 like nucleolar associated transcriptional repressor； nucleolar complex protein 2 homolog； NOC2-like protein； NOC2L nucleolar associated transcriptional repressor； novel INHAT (inhibitor of histone acetyltransferase) repressor； novel INHAT repressor； nucleolar complex associated 2 homolog； protein NOC2 homolog； protein phosphatase 1, regulatory subunit 12； NOC2家族样蛋白；

背景信息：

NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.