基因名：
FBXL5
产品别名：
FBL4； FBL5； FLR1； FBXL5； F-box and leucine rich repeat protein 5； F-box and leucine rich repeat protein 5； F-box/LRR-repeat protein 5； F-box protein FBL4/FBL5； p45SKP2-like protein； FBXL5蛋白；
背景信息：
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
