基因名：
Dapp1
产品别名：
Bam32； Dapp1； dual adaptor for phosphotyrosine and 3-phosphoinositides 1； dual adaptor for phosphotyrosine and 3-phosphoinositides 1； dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide； B-cell adapter molecule of 32 kDa； b lymphocyte adapter protein Bam32； B淋巴细胞衔接分子DAPP1； 短链脱氢还原酶1； 磷酸化B淋巴细胞衔接分子DAPP1； 酪氨酸3-磷酸肌醇双衔接因子(DAPP1)；
背景信息：
DHRS1 (dehydrogenase/reductase (SDR family) member 1), also known as SDR19C1, is a 313 amino acid protein that belongs to the short-chain dehydrogenases/reductases (SDR) family and likely functions as an oxidoreductase. Abundantly expressed in heart and liver, DHRS1 contains an SDR motif and is encoded by a gene that maps to human chromosome 14q12. Human chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
