JNJ-41443532 Free Base is a CCR2 receptor antagonist. It is used for the orally bioavailable treatment of type-2 diabetes mellitus. A phase I trial in healthy volunteers was completed in Belgium, and a phase II trial in patients with type 2 diabetes was completed in the US. References: Di Prospero NA, Artis E, Andrade-Gordon P, Johnson DL, Vaccaro N, Xi L, Rothenberg P. CCR2 antagonism in patients with type 2 diabetes mellitus: a randomized, placebo-controlled study. Diabetes Obes Metab. 2014 Nov;16(11):1055-64. doi: 10.1111/dom.12309. Epub 2014 May 25. PubMed PMID: 24798870.
纯度:≥98%
CAS:1228650-83-6