基因名:
Racgap1
产品别名:
AI227039; AI327394; Band25; GTPase; MgcRacGAP; gtl11; mKIAA1478; Racgap1; Rac GTPase-activating protein 1; Rac GTPase-activating protein 1; rac GTPase-activating protein 1; male germ cell RacGap; Rac-GTP酶激活蛋白1(RACGAP1); Rho GTP酶激活蛋白GAP; 磷酸化Rho GTP酶激活蛋白GAP;
背景信息:
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.