JNJ-42259152 is a novel phosphodiesterase 10A PET tracer. Kinetic modeling of (18)F-JNJ-42259152 shows that PDE10A activity can be reliably quantified and simplified using a reference tissue model with the frontal cortex as reference and a 60-min acquisition period. References: Van Laere K, Ahmad RU, Hudyana H, Dubois K, Schmidt ME, Celen S, Bormans G, Koole M. Quantification of 18F-JNJ-42259152, a novel phosphodiesterase 10A PET tracer: kinetic modeling and test-retest study in human brain. J Nucl Med. 2013 Aug;54(8):1285-93. doi: 10.2967/jnumed.112.118679. Epub 2013 Jul 10. PubMed PMID: 23843566.

纯度：≥98%

CAS：1301167-87-2