基因名:
FOXP1
产品别名:
12CC4; HSPC215; MFH; QRF1; hFKH1B; FOXP1; forkhead box P1; forkhead box P1; forkhead box protein P1; fork head-related protein like B; glutamine-rich factor 1; mac-1-regulated forkhead; 叉头框蛋白P1(FOXP1); 叉头蛋白P1;
背景信息:
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]