基因名:
BBC3
产品别名:
JFY-1; JFY1; PUMA; BBC3; BCL2 binding component 3; BCL2 binding component 3; bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; p53-upregulated modulator of apoptosis; p53上调凋亡调节因子(PUMA); p53正向细胞凋亡调控因子;
背景信息:
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.