基因名:
VPS4A
产品别名:
CIMDAG; SKD1; SKD1A; SKD2; VPS4; VPS4-1; VPS4A; vacuolar protein sorting 4 homolog A; vacuolar protein sorting 4 homolog A; vacuolar protein sorting-associated protein 4A; SKD1-homolog; hVPS4; vacuolar protein sorting factor 4A; vacuolar sorting protein 4; 液泡分选蛋白4;
背景信息:
Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment. May be involved in the release of components of the bilayered coat from the endosomal membrane. The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex. In case of infection, the HIV-1 virus takes advantage of it for budding and exocytic cargos of viral proteins.