基因名:
Dok3
产品别名:
AI450713; Dokl; Dok3; docking protein 3; docking protein 3; docking protein 3; DOK-L; Dok-like protein; downstream of tyrosine kinase 3; p62(dok)-like protein; p62Dok-like protein; 停靠蛋白3(DOK3); 对接蛋白3;
背景信息:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing.