基因名：
Abcg5
产品别名：
cmp； sterolin-1； trac； Abcg5； ATP binding cassette subfamily G member 5； ATP binding cassette subfamily G member 5； ATP-binding cassette sub-family G member 5； ATP-binding cassette, sub-family G (WHITE), member 5； sterolin 1； ATP结合盒转运蛋白G5(ABCG5)； 三磷酸腺苷结合转运蛋白G超家族成员5；
背景信息：
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
