基因名:
NTMT1
产品别名:
AD-003; C9orf32; HOMT1A; METTL11A; NRMT; NRMT1; NTM1A; NTMT1; N-terminal Xaa-Pro-Lys N-methyltransferase 1; N-terminal Xaa-Pro-Lys N-methyltransferase 1; N-terminal Xaa-Pro-Lys N-methyltransferase 1; N-terminal RCC1 methyltransferase; X-Pro-Lys N-terminal protein methyltransferase 1A; alpha N-terminal protein methyltransferase 1A; methyltransferase-like protein 11A; 甲基化样蛋白11(N端);
背景信息:
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala, Pro or Ser residue in the [Ala/Pro/Ser]-Pro-Lys motif. Mediates the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation.