基因名：
ZBTB44
产品别名：
BTBD15； HSPC063； ZNF851； ZBTB44； zinc finger and BTB domain containing 44； zinc finger and BTB domain containing 44； zinc finger and BTB domain-containing protein 44； BTB (POZ) domain containing 15； BTB/POZ domain-containing protein 15； zinc finger protein 851； 锌指蛋白851；
背景信息：
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying protein. ZBTB44 is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.
