基因名:
Tnfrsf19
产品别名:
AL023044; AW123854; TAJ; TAJ-ALPHA; TRADE; Troy; Tnfrsf19; tumor necrosis factor receptor superfamily, member 19; tumor necrosis factor receptor superfamily, member 19; tumor necrosis factor receptor superfamily member 19; Toxicity and JNK inducer; 肿瘤坏死因子受体超家族成员19(TNFRSF19); 肿瘤坏死因子配体超家族成员19;
背景信息:
TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.