基因名:
SERTAD1
产品别名:
SEI1; TRIP-Br1; TRIPBR1; SERTAD1; SERTA domain containing 1; SERTA domain containing 1; SERTA domain-containing protein 1; CDK4-binding protein p34SEI; CDK4-binding protein p34SEI1; SEI-1; p34(SEI-1); transcriptional regulator interacting with the PHD-bromodomain 1; 调控周期蛋白依赖蛋白激酶SEI1;
背景信息:
Sertad1 acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).