基因名：
CERS2
产品别名：
L3； LASS2； SP260； TMSG1； CERS2； ceramide synthase 2； ceramide synthase 2； ceramide synthase 2； LAG1 homolog, ceramide synthase 2； LAG1 longevity assurance 2； longevity assurance (LAG1, S. cerevisiae) homolog 2； sphingosine N-acyltransferase CERS2； tumor metastasis-suppressor gene 1 protein； very-long-chain ceramide synthase CERS2； 肿瘤转移抑制基因1； 长寿保证同源物2(LASS2)；
背景信息：
LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
