基因名:
dbx2
产品别名:
hlx3; zgc:110519; dbx2; developing brain homeobox 2; developing brain homeobox 2; developing brain homeobox 2; homeobox protein DBX2; H2.0-like homeobox 3; 大脑发育同源蛋白2; 脑发育同源蛋白2;
背景信息:
DBX2 is a 339 amino acid member of the H2.0 homeobox family. DBX2, which is localized to the nucleus, contains one homeobox DNA-binding domain, a region of 60 amino acids that binds DNA through a helix-turn-helix type of structure. DBX2, which is expressed in the forebrain, midbrain, hindbrain and spinal cord, has been implicated in CNS development.Specifically, DBX2 has been shown to play a role in spinal cord dorsal/ventral patterning, as well as the regionalization of the CNS. DBX2 is also thought to play a role in the production of multiple spinal cord cell types.