基因名：
Atg4a
产品别名：
APG4； ATG4； AUT2； Atg4； CG4428； Dmel\CG4428； atg4； Atg4a； Autophagy-related 4a； Autophagy-related 4a； Autophagy-related 4a； Atg4a-PA； Atg4a-PB； Autophagy-specific gene 4； Autophagy-specific gene 4a； CG4428-PA； CG4428-PB； 磷酸化自噬相关蛋白4A； 自噬相关蛋白4A；
背景信息：
Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
