基因名：
Atg10
产品别名：
ATG10； CG12821； Dmel\CG12821； Atg10； Autophagy-related 10； Autophagy-related 10； Autophagy-related 10； Atg10-PB； Atg10-PD； Autophagy-specific gene 10； CG12821-PB； CG12821-PD； 自噬相关蛋白10； 自噬相关蛋白10(ATG10)；
背景信息：
Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.
