基因名：
APH1A
产品别名：
6530402N02Rik； APH-1； APH-1A； CGI-78； APH1A； aph-1 homolog A, gamma-secretase subunit； aph-1 homolog A, gamma-secretase subunit； gamma-secretase subunit APH-1A； APH1A gamma secretase subunit； anterior pharynx defective 1 homolog A； aph-1alpha； presenilin-stabilization factor； 早老素γ分泌酶；
背景信息：
APH1a is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Belongs to the APH-1 family.
