基因名:
INSIG2
产品别名:
INSIG-2; INSIG2; insulin induced gene 2; insulin induced gene 2; insulin-induced gene 2 protein; INSIG2 membrane protein; insulin induced protein 2; 胰岛素诱导基因2;
背景信息:
Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.