基因名:
CLEC1B
产品别名:
1810061I13Rik; CLEC2; CLEC2B; PRO1384; QDED721; CLEC1B; C-type lectin domain family 1 member B; C-type lectin domain family 1 member B; C-type lectin domain family 1 member B; C-type lectin-like receptor 2; C型凝集素结构域家族1成员B;
背景信息:
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]