基因名:
UBAP1
产品别名:
NAG20; SPG80; UAP; UBAP; UBAP-1; UBAP1; ubiquitin associated protein 1; ubiquitin associated protein 1; ubiquitin-associated protein 1; nasopharyngeal carcinoma-associated gene 20 protein; 泛素关联蛋白1(UBAP1); 泛素相关蛋白1;
背景信息:
Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family. Members of this family are related to ubiquitin and the ubiquitination pathway. Because of their cytogenetic location, this UBA domain family member is being studied as a putative target for mutation in nasopharyngeal carcinomas. UBAP1 is highly expressed in the heart, brain, placenta, lung, skeletal muscle, liver, and pancreas. UBAP1 consists of two UBA domains and one UMA domain. The ubiquitin associated domain is throught to be a non-covalent ubiquitin binding domain, including a compact three helix bundle.