基因名:
TLR7
产品别名:
IMD74; SLEB17; TLR7-like; TLR7; toll like receptor 7; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; Toll样受体7(TLR7); Toll样受体7蛋白;
背景信息:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.