基因名:
CYP39A1
产品别名:
CYP39A1; cytochrome P450 family 39 subfamily A member 1; cytochrome P450 family 39 subfamily A member 1; 24-hydroxycholesterol 7-alpha-hydroxylase; cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1; 胆固醇24α7羟化酶;
背景信息:
The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.