基因名:
ANAPC5
产品别名:
APC5; ANAPC5; anaphase promoting complex subunit 5; anaphase promoting complex subunit 5; anaphase-promoting complex subunit 5; cyclosome subunit 5; 细胞分裂周期蛋白5;
背景信息:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.