基因名:
PALS2
产品别名:
MPP6; VAM-1; VAM1; p55T; PALS2; protein associated with LIN7 2, MAGUK p55 family member; protein associated with LIN7 2, MAGUK p55 family member; protein PALS2; MAGUK p55 subfamily member 6; MAGUK protein p55T; VELI-associated MAGUK 1; membrane palmitoylated protein 6; membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); protein associated with LIN7 2, MAGUK family member; protein associated with Lin7 2; 棕榈酰化膜蛋白6; 棕榈酰化膜蛋白6(MPP6);
背景信息:
Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. VAM1 or MPP6 is thought to be a nucleolus specific exosome co factor, required for its role in the maturation of 5.8S rRNA.