重组宫颈癌抑制蛋白4

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重组宫颈癌抑制蛋白4

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant MAP3K20
Recombinant mitogen-activated protein kinase kinase kinase 20 protein

基因名：

MAP3K20

产品别名：

AZK； CNM6； MLK7； MLT； MLTK； MLTKalpha； MLTKbeta； MRK； SFMMP； ZAK； mlklak； pk； MAP3K20； mitogen-activated protein kinase kinase kinase 20； mitogen-activated protein kinase kinase kinase 20； mitogen-activated protein kinase kinase kinase 20； HCCS-4； MLK-like mitogen-activated protein triple kinase； ZAK1 homolog, leucine zipper and sterile-alpha motif kinase； human cervical cancer suppressor gene 4 protein； mitogen-activated protein kinase kinase kinase MLT； mixed lineage kinase 7； mixed lineage kinase with a leucine zipper and a sterile alpha motif； mixed lineage kinase-related kinase MRK-beta； sterile alpha motif and leucine zipper containing kinase AZK；宫颈癌抑制蛋白4；

背景信息：

Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.