基因名：
MYOZ2
产品别名：
C4orf5； CMH16； CS-1； FATZ-2； MYOZ2； myozenin 2； myozenin 2； myozenin-2； FATZ-related protein 2； calcineurin-binding protein calsarcin-1； muscle-specific protein； 肌原调节蛋白2(MYOZ2)； 肌肉特异性蛋白MYOZ2；
背景信息：
Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder.
