基因名:
Agpat5
产品别名:
1110013A05Rik; D8Ertd319e; Agpat5; 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon); 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon); 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon; 1-AGP acyltransferase 5; 1-AGPAT 5; LPAAT-epsilon; lysophosphatidic acid acyltransferase epsilon; 溶血磷脂酰基转移酶5;
背景信息:
Phosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction. LPAAT-epsilon (lysophosphatidic acid acyltransferase epsilon, also designated 1-AGP acyltransferase 5 (AGPAT5)) catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid. LPAAT-epsilon is a membrane-bound protein belonging to the LPAAT family. Members of the LPAAT family have a well-known role in lipid biosynthesis and they may also play a role in tumor progression. LPAAT-epsilon is expressed in a tissue-specific manner in prostate and testis. LPAAT-epsilon is most closely related to AGPAT8, which is highly expressed in heart.