基因名:
FGFRL1
产品别名:
FGFR-5; FGFR5; FHFR; FGFRL1; fibroblast growth factor receptor like 1; fibroblast growth factor receptor like 1; fibroblast growth factor receptor-like 1; FGF homologous factor receptor; FGF receptor-like protein 1; FGFR-like protein; fibroblast growth factor receptor 5; 成纤维细胞生长因子受体5; 成纤维细胞生长因子受体样蛋白1(FGFRL1);
背景信息:
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.