基因名：
DCUN1D1
产品别名：
DCNL1； DCUN1L1； RP42； SCCRO； SCRO； Tes3； DCUN1D1； defective in cullin neddylation 1 domain containing 1； defective in cullin neddylation 1 domain containing 1； DCN1-like protein 1； DCN1, defective in cullin neddylation 1, domain containing 1； DCUN1 domain-containing protein 1； RP42 homolog； defective in cullin neddylation protein 1-like protein 1； squamous cell carcinoma-related oncogene； 鳞状细胞癌相关蛋白；
背景信息：
DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
