基因名：
TREM1
产品别名：
CD354； TREM-1； TREM1； triggering receptor expressed on myeloid cells 1； triggering receptor expressed on myeloid cells 1； triggering receptor expressed on myeloid cells 1； triggering receptor expressed on monocytes 1； TREM1蛋白； 髓系细胞触发受体1； 髓细胞触发受体1(TREM1)； 髓细胞触发受体1(TREM1)真核蛋白；
背景信息：
Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. Human TREM-1 shares 42% sequence homology with mouse TREM-1.
