基因名:
KRT20
产品别名:
CD20; CK-20; CK20; K20; KRT21; KRT20; keratin 20; keratin 20; keratin, type I cytoskeletal 20; cytokeratin 20; keratin 20, type I; protein IT; 半胱氨酸蛋白酶8; 细胞角蛋白20; 角蛋白20(CK 20);
背景信息:
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.