基因名:
DGCR8
产品别名:
C22orf12; DGCRK6; Gy1; pasha; DGCR8; DGCR8 microprocessor complex subunit; DGCR8 microprocessor complex subunit; microprocessor complex subunit DGCR8; DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; 狄乔治(DiGeorge)氏综合征相关蛋白8;
背景信息:
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]