基因名:
OTULINL
产品别名:
FAM105A; NET20; OTULINL; OTU deubiquitinase with linear linkage specificity like; OTU deubiquitinase with linear linkage specificity like; inactive ubiquitin thioesterase OTULINL; family with sequence similarity 105 member A; inactive ubiquitin thioesterase FAM105A; protein FAM105A; FAM105A蛋白;
背景信息:
With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. The FAM105A gene product has been provisionally designated FAM105A pending further characterization.