基因名:
UBR7
产品别名:
C14orf130; LICAS; UBR7; ubiquitin protein ligase E3 component n-recognin 7; ubiquitin protein ligase E3 component n-recognin 7; putative E3 ubiquitin-protein ligase UBR7; N-recognin-7; RING-type E3 ubiquitin transferase UBR7; ubiquitin protein ligase E3 component n-recognin 7 (putative); 14号染色体开放阅读框130;
背景信息:
Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.