基因名：
TRIM62
产品别名：
DEAR1； TRIM62； tripartite motif containing 62； tripartite motif containing 62； E3 ubiquitin-protein ligase TRIM62； RING-type E3 ubiquitin transferase TRIM62； ductal epithelium-associated RING Chromosome 1； tripartite motif-containing protein 62； TRIM62蛋白；
背景信息：
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM58 (tripartite motif containing 58), also known as BIA2, is a 486 amino acid protein that belongs to the TRIM/RBCC family and contains one B box-type zinc finger, a RING-type zinc finger and a single B30.2/SPRY domain. The gene encoding TRIM58 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
