基因名:
BRIX1
产品别名:
BRIX; BXDC2; BRIX1; biogenesis of ribosomes BRX1; biogenesis of ribosomes BRX1; ribosome biogenesis protein BRX1 homolog; BRX1, biogenesis of ribosomes, homolog; brix domain containing 2; brix domain-containing protein 2; BXDC2蛋白;
背景信息:
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.