基因名:
GIMAP4
产品别名:
IAN-1; IAN1; IMAP4; MSTP062; GIMAP4; GTPase, IMAP family member 4; GTPase, IMAP family member 4; GTPase IMAP family member 4; human immune associated nucleotide 1; immune-associated nucleotide-binding protein 1; immunity associated protein 4; immunity-associated nucleotide 1 protein; GTP酶IMAP家族成员4;
背景信息:
Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.
Tissue specificity:
Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.